Causes of xerostomia
Medications are the leading cause of dry mouth. Over 400 different medications have been associated with xerostomia1,3,4 and additionally taking more than one medication significantly increases the chance of having dry mouth.
Common medications associated with dry mouth include:
- Tricyclic antidepressants
- Beta blockers
b. Cancer treatment
Cancer treatment often requires procedures such as surgery, radiotherapy and chemotherapy, all of which can damage salivary tissue and may have a dramatic effect on salivary flow. In the most severe case, this can result in a total loss of salivary output.
c. Systemic disease
Dry mouth can also occur as a result of a number of systemic diseases, the main autoimmune inflammatory disease being Sjögren's syndrome.